Caitlyn 2XKO combo: 457 damage, easy, by Katsugami. This is an easy combo to execute. The only requirement is to start with 2M, then M to confirm into H.…
2M > M > H > j.M > j.H > J.4S2 > J.H > M > H > j.M > j.H > J.S1 > j.S2 > S1+L
This is an easy combo to execute. The only requirement is to start with 2M, then M to confirm into H. Since the opponent is airborne, you can jump, which allows you to easily reach the correct height to catch them during the fall after the 2S2 launch. You can finish with S1+L; be sure to read the fall trajectory carefully to hit them properly. Alternatively, you can end with S2+M to set up the next neutral.